Push the door button on the AutoTouch™ reusable autoinjector and insert the Enbrel Mini™ cartridge. It should slide freely and completely into the door. Choose an injection site on your body (eg, thigh, abdomen or stomach area, or upper arm). Remove the needle cap when you are ready to inject.Click to see full answer. Hereof, where do you inject etanercept?The best place to inject etanercept injection is the front of your middle thighs. You can also inject the medication in your lower stomach below your navel, except the area 2 inches (5 centimeters) around your navel.One may also ask, how do you administer an Enbrel pen? When the needle is completely inserted into the skin, let go of the skin that you are holding. With your free hand, hold the syringe near its base to stabilize it. Then push the plunger to inject all of the Enbrel solution at a slow, steady rate. Also asked, how is etanercept given? Enbrel (etanercept) injection is supplied as a clear and colorless sterile, preservative-free solution for subcutaneous administration in single-dose prefilled syringes and an Enbrel single-dose prefilled SureClick autoinjector with a 27-gauge, ½-inch needle.How often is Enbrel administered?Enbrel is given as a subcutaneous injection, usually once a week. If you have rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis, the standard Enbrel dose is one 50-mg injection every week. For adults with plaque psoriasis, you may start out with a dose of 50 mg twice per week for the first 3 months.