Splenda usually contains 95% dextrose (D-glucose) and maltodextrin (by volume) which the body readily metabolizes, combined with a small amount of mostly indigestible sucralose. Sucralose is made by replacing three select hydrogen-oxygen groups on sucrose (table sugar) molecules with three chlorine atoms.Click to see full answer. Moreover, does Splenda have sugar in it?Sucralose is calorie-free, but Splenda also contains the carbohydrates dextrose (glucose) and maltodextrin, which brings the calorie content up to 3.36 calories per gram ( 1 ). Splenda is the most popular product made from it. Sucralose is made from sugar but contains no calories and is much sweeter.Secondly, is Splenda bad for your health? In 1999 The U.S. Food and Drug Administration (FDA) approved sucralose as safe for human consumption as a general sweetener. Sucralose may increase blood glucose and insulin levels: Sucralose may negatively affect the very people who are using it to decrease sugar consumption and stabilize blood glucose levels. Accordingly, is Splenda better for you than sugar? Sucralose is 600 times as sweet as sugar, and stevia is 200-400 times as sweet, so less Splenda is needed initially to satisfy the palette. Over time, however, high-intensity sweeteners change how the brain responds to sweet tastes and can increase overall sweet cravings.What is the bad ingredient in Splenda? The Dangers of Sucralose Sucralose, often sold under the brand name Splenda, is one of the most commonly used artificial sweeteners on the market. In addition to sucralose, other Splenda ingredients include maltodextrin, sugar and soluble corn fiber, depending on which product you choose.